多糖类:对它们的免疫调节作用的审查
Liping Chen1, Xiao Liu2, Kaiyue Zheng2
1School of Comprehensive Health Management, Xihua University, Chengdu 610097, China.
Molecules (Basel, Switzerland)
|November 9, 2024
概括
主要来自Cordyceps sinensis和militaris的Cordyceps多糖体显示出显著的免疫调节作用. 这些化合物增强了免疫细胞的活性,有望减轻免疫抑制和瘤逃避.
科学领域:
- 菌类学 菌类学是指菌类学.
- 免疫学 免疫学 免疫学
- 药理学 药理学是指药理学的学科.
背景情况:
- 科尔迪塞普斯真菌是寄生虫虫,具有多样化的药理学活动.
- 多糖是 Cordyceps 中的主要活性成分,以其免疫调节作用而闻名.
- 像Cordyceps sinensis和Cordyceps militaris这样的Cordyceps物种是这些活性多糖的主要来源.
研究的目的:
- 审查关于Cordyceps多糖的免疫调节作用的研究进展.
- 提供关于基于Cordyceps多糖的免疫调节的有价值的参考信息.
主要方法:
- 在科学网络数据库中使用关键字搜索:cordyceps,多糖,免疫调节.
- 在2004年至2024年间发表的收集和审查的研究.
- 不包括低影响力和低工作负载的物品.
主要成果:
- 科迪塞普斯多糖增加了巨细胞,淋巴细胞和树突细胞的活性.
- 它们促进免疫活性物质如细胞因子和化学因子的表达.
- 动物研究证实了它们改善药物/辐射诱导的免疫抑制,增强免疫器官指数和减轻瘤免疫逃避的能力.
结论:
- 科迪塞普斯多糖具有显著的免疫调节活性.
- 对其治疗潜力的进一步研究是有必要的.
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