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Updated: Jun 7, 2025

Isolation of Intermediate Filament Proteins from Multiple Mouse Tissues to Study Aging-associated Post-translational Modifications
09:29

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Published on: May 18, 2017

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针对TBK1介导的ATAD3A酸化改善了与衰老相关的病理

Yujiao He1, Yanchen Liu1, Mingyue Zheng1

  • 1Guangdong Cardiovascular Institute, Medical Research Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|November 9, 2024
PubMed
概括

科学家们发现了一条涉及TBK1-ATAD3A-Pink1的新途径,该途径驱动细胞衰老. 抑制这种途径可以减少衰老的表型,并提高癌症化疗的敏感性.

关键词:
的 TBK1 - ATAD3A 轴.抗衰老疗法是一种治疗方法.细胞衰老 细胞衰老化疗 化疗是一种化学疗法.线粒细胞衰变 (mitophagy) 是一种神经衰变的过程.

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