合成和评估化Piperazine-Hydroxyethylamine类似物作为潜在的抗等离体候选物

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Microwave-Assisted Preparation of 1-Aryl-1H-pyrazole-5-amines
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Charu Upadhyay1, Shreya Bhattacharya2, Sumit Kumar1

  • 1Department of Chemistry, Miranda House, University of Delhi, Delhi, 110007.

ChemMedChem
|November 9, 2024
PubMed
概括

新的化皮佩拉津-基乙烯胺类同类物被合成并对疟疾寄生虫进行了测试. 化合物13g和14g显示出强烈的抗疟疾活性,并在小鼠模型中有效,表明新药开发的潜力.

关键词:
疟疾:疟疾是一种疾病.原菌 (Plasmodium falciparum) 是一种有毒的病毒.抗疟疾药物可以.化基乙胺衍生物的化基乙胺衍生物肝脏阶段 肝脏阶段

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