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对比手术内注射和办公室内注射的类固醇,用于管理小肠缩症

Fatemeh Ramazani¹, J Douglas Bosch¹, Derrick R Randall¹

¹Section of Otolaryngology-Head and Neck Surgery, Department of Surgery, University of Calgary, Calgary, Alberta, Canada.

The Laryngoscope

|November 9, 2024

概括

皮质类固醇注射用于下喉狭窄症 (SGS) 并没有改善无手术间隔 (SFI). 连续内伤性类固醇注射 (SILSI) 对异常性SGS患者也没有显著的益处.

科学领域:

耳鼻喉科耳鼻喉科耳鼻喉科
儿科手术儿科手术
呼吸系统医学呼吸系统医学

背景情况:

肠下狭窄症 (SGS) 的管理旨在延长无手术间隔 (SFI).
内溶性皮质类固醇注射是改善SGS患者SFI的拟议方法.

研究的目的:

根据治疗方式,比较异常性SGS (iSGS) 患者的SFI.
评估单独进行内镜扩张的疗效与使用外科内皮质类固醇注射进行扩张的疗效,以及使用连续内伤类固醇注射 (SILSI) 进行扩张的疗效.

主要方法:

在2012年至2023年期间接受了305项手术的104名iSGS患者的回顾性审查.
从手术干预日期计算的无手术间隔 (SFI).
独立样本中位数测试用于治疗组之间的统计比较.

主要成果:

仅通过内镜扩张,与单次手术内类固醇注射 (395天) 相比,SFI的中位数更长 (658天).
接受单次手术内类固醇注射的患者的SFI比仅接受扩张治疗的患者要短得多 (p=0.001).
在初始扩张和手术内注射后过渡到连续内伤类固醇注射 (SILSI),导致SFI在统计学上显著下降 (p=0.032).

结论:

与仅仅扩张相比,单次手术内皮质类固醇注射与iSGS患者的无手术间隔较短有关.
连续内伤性类固醇注射 (SILSI) 对该患者群体的SFI没有显著改善.

关键词:

扩张扩张是什么类型: 类型: 类型: 类型: 类型: 类型: 类型: 类型: 类型: 类型: 类型: 类型: 类型: 类型: 类型: 类型: 类型: 类型: 类型: 类型: 类型: 类型: 类型: 类型: 类型:在 subglottic 狭窄症.

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