住院高级心力衰竭与保留与减少的左心室射出分数:全球视角
Vasiliki Bistola1, Dimitrios Farmakis1, Jasper Tromp2
1Department of Cardiology, Attikon University Hospital, National Kapodistrian University of Athens Medical School, Athens, Greece.
JACC. Heart failure
|November 9, 2024
概括
住院的晚期心力衰竭 (HF) 患者保留喷射分数的结果与减少喷射分数的患者有相似的结果. 低收入国家使用较少的HF治疗,死亡率更高.
科学领域:
- 心脏病学 心脏病学
- 心脏衰竭研究研究
- 临床试验 临床试验
背景情况:
- 心力衰竭 (HF) 的结果和先进的HF特征可以根据左心室喷射率 (LVEF) 和地理区域在全球范围内有所不同.
- 了解这些变化对于有效的高频管理至关重要.
研究的目的:
- 分析住院高级HF患者在LVEF频谱中的特征和结果.
- 调查高级HF患者个人资料和治疗中的基于收入的区域和国家差异.
主要方法:
- 来自全球REPORT-HF注册表的18553名住院急性HF患者的分析.
- 专注于3397名晚期HF患者 (根据先前的诊断,严重的症状和最近的HF住院情况来定义).
- 根据LVEF (减少,轻度/中度减少,保留),世界地区和国家收入水平进行子组分析.
主要成果:
- 晚期HF患者的LVEF分布有所变化 (44.5%严重减少,34.9%轻度/中度减少,20.7%保持).
- 一年死亡率因地区不同 (东欧为23%,东南亚为37%).
- 来自中低收入国家的患者经历了较高的一年死亡率 (34%) 与高收入国家 (26-27%) 相比,贝塔阻断剂和高频器件的使用较少. 调整后的死亡风险在LVEF子组中是相似的.
结论:
- 住院的高级HF患者保持LVEF面临类似的不良结果与那些减少LVEF.
- 低中等收入国家在HF治疗实施方面存在差异,因此一年死亡率更高.
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