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在正常受试者和使用隐形眼镜传感器系统的开放角度眼光病患者中,随着位置转换而持续的眼内压变化

Yuning Zhang¹, Wenxin Yang¹, Zidong Chen¹

¹State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Sun Yat-Sen University, Guangzhou, 510060, People's Republic of China.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie

|November 9, 2024

概括

一个新型的隐形眼镜传感器系统 (CLS) 能够有效地监测定位变化期间眼内压力 (IOP) 的变化. 玻璃眼病患者的内血压增加比正常人更明显,与眼睛高血压患者不同.

科学领域:

眼科医生眼科眼科
生物医学工程生物医学工程
玻璃眼研究研究玻璃眼研究

背景情况:

位置变化可以改变眼内压力 (IOP),其中的变化可能与青光眼有关.
传统的度仪提供了不连续的IOP测量,限制了对动态IOP变化的理解.
一个新的隐形眼镜传感器系统 (CLS) 在位置转换期间提供连续的IOP监控.

研究的目的:

评估新型CLS在检测定位过渡期间连续IOP变化的有效性.
为了比较正常受试者,未经治疗的青光眼 (高压和正常压) 和未经治疗的眼睛高血压 (OHT) 组中的IOP变异模式.

主要方法:

一项前性比较研究,涉及正常受试者,高压格拉瘤 (HTG),正常张力格拉瘤 (NTG) 和OHT患者.
在连续的身体姿势变化期间使用CLS进行持续的IOP监测:坐着,躺着和10°的头向下倾斜 (HDT).
分析IOP参数,包括位置和组之间的平均值,峰值,波动,增量,间隔和速度.

主要成果:

与坐着患者相比,CLS检测出正常受试者,HTG和NTG患者的卧卧/HDT姿势中增加的平均和峰值IOP.
除了速度之外,OHT受试者在不同位置上没有显著的IOP参数差异.
在坐卧转变期间,HTG患者表现出比正常人更高的IOP增量和速度;NTG患者与正常人相比没有显著差异.

结论:

在CLS有效地记录了持续的IOP对正常眼睛和眼睛的位置变化的反应.
从坐到仰卧的过渡增加了正常受试者的内压,HTG和NTG,但不是OHT.
过渡后的IOP增加在HTG患者中比正常人更明显和更快,而在NTG患者中则相似.

关键词:

身体的位置身体的位置隐形眼镜的隐形眼镜是一个隐形眼镜.眼光障碍眼光障碍眼光障碍眼光障碍眼内压力眼内压力

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