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Updated: Jun 7, 2025

Co-immunoprecipitation Assay Using Endogenous Nuclear Proteins from Cells Cultured Under Hypoxic Conditions
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Co-immunoprecipitation Assay Using Endogenous Nuclear Proteins from Cells Cultured Under Hypoxic Conditions

Published on: August 2, 2018

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低氧诱导因子 (HIF-1alpha) 的分子对接和分子动力学:向潜在的抑制剂

Dina Reda1, Abdo A Elfiky2, M Elnagdy3

  • 1Medical Biophysics, Department of Physics, Faculty of Science, Helwan University, Cairo, Egypt.

Journal of biomolecular structure & dynamics
|November 9, 2024
PubMed
概括

新的抗癌药物尼罗丁尼和皮尼迪对HIF-1α具有很高的结合亲和力,HIF-1α是癌细胞适应低氧的关键调节剂. 这些化合物显示出有前途的分子动力学和安全性,需要进一步研究.

关键词:
这就是HIF-1alpha.分子对接是分子对接.抑制剂 抑制剂 抑制剂分子动力学分子动力学瘤缺氧 瘤缺氧

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