高强度间歇训练对PTSD患者血清脑源性神经营养因子的影响
Annabell Jäger1, Anima Pieper1, Kathlen Priebe1
1Charité Universitätsmedizin Berlin, Department of Psychiatry and Neurosciences, CCM, Charitéplatz 1, 10117, Berlin, Germany.
Journal of psychiatric research
|November 9, 2024
概括
高强度间歇训练 (HIIT) 在患有PTSD的个体中暂时增加了血清脑衍生神经营养因子 (BDNF). 然而,无论是HIIT还是低强度训练 (LIT),都没有在12天内增加BDNF水平.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 运动生理学 运动生理学
背景情况:
- 大脑衍生神经营养因子 (BDNF) 对突触可塑性和记忆形成至关重要.
- 血清BDNF水平降低与精神疾病有关,包括创伤后应激障碍 (PTSD).
- 身体炼因其提高血清BDNF的潜力而得到认可.
研究的目的:
- 确定最佳的运动方案,以增加血清BDNF在患有PTSD的个体.
- 为了比较高强度间歇训练 (HIIT) 与低强度训练 (LIT) 对BDNF释放的影响.
- 为了测试这种假设,即更高强度的运动会产生更大的BDNF增加.
主要方法:
- 40名患有PTSD的参与者被随机分配到HIIT或LIT组进行12天的干预.
- 在第一次和最后的干预日,测量了运动前和运动后的血清BDNF水平.
- 在BDNF水平评估中控制了血小板计数.
主要成果:
- 一次HIIT训练会导致HIIT组血清BDNF的显著增加,尽管是暂时的.
- 这种在HIIT后BDNF的短暂增加在两个测量日都被观察到,即使在对血小板进行控制后也是如此.
- 在12天的训练期间,HIIT和LIT协议都没有导致血清BDNF持续增加.
结论:
- 高强度间歇训练 (HIIT) 可以在被诊断患有PTSD的个体中急剧提高血清BDNF水平.
- 在单次HIIT训练后观察到的BDNF增加是暂时的.
- 在12天的干预期间,HIIT和LIT都没有在提高血清BDNF水平方面表现出有效性.
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