过敏疾病与精神健康状况之间的关联:一个总体审查
Xianpeng Xu1, Sha Li1, Yingjie Chen1
1Chengdu University of Traditional Chinese Medicine, Chengdu and the Department of Otolaryngology-Head and Neck Surgery, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
The Journal of allergy and clinical immunology
|November 9, 2024
概括
过敏性疾病,特别是喘,与患ADHD和抑郁症等精神健康状况的风险更高有关. 需要进一步的研究来确认因果关系并了解这些关联.
科学领域:
- 免疫学 免疫学 免疫学
- 精神病学是一个精神病学.
- 流行病学 流行病学
背景情况:
- 过敏性疾病和精神健康状况之间的关系需要进一步调查,因为影响的一致性和程度不明确.
- 现有的研究已经探索了这些联系,但需要进行全面的评估,以建立明确的证据层次.
研究的目的:
- 系统地评估有关过敏性疾病和精神健康状况的已发表证据.
- 为这些协会建立一个新的证据层次.
- 确定该领域的研究缺口.
主要方法:
- 进行了系统性审查与元分析的综合审查.
- 搜索了主要的数据库 (PubMed,Embase,科学网,Cochrane) 到2024年4月.
- 使用AMSTAR 2评估方法质量和计算总结效果估计.
主要成果:
- 确定了21项符合条件的系统审查,检查了超过3.48亿个人的37个协会.
- 有令人信服的证据将喘与ADHD风险增加联系在一起 (OR 1.34).
- 强有力的证据将过敏性鼻炎与和睡眠障碍联系起来,食物过敏与自闭症谱系障碍联系在一起,而亚托皮炎与抑郁症,焦虑症,多动症和自杀念头联系在一起.
结论:
- 过敏性疾病与各种心理健康状况的风险增加有关,喘显示最有力的证据.
- 这些关联不证实因果关系,显著的异质性需要高质量的初级研究.
- 进一步的研究至关重要,以确定因果关系,并加强过敏疾病与心理健康联系的证据基础.
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