在接受血造干细胞移植的患者内牙治疗:一项回顾性队列研究
Maria Emília Mota1, José F Siqueira2, Isabela N Rôças2
1Stomatology Department, School of Dentistry, University of São Paulo, São Paulo, Brazil; Department of Oral Medicine, A.C. Camargo Cancer Center, São Paulo, Brazil.
Journal of endodontics
|November 9, 2024
概括
根管治疗 (RCT) 在接受血造干细胞移植 (HSCT) 的患者中有效管理顶端牙周炎 (AP). 这种必不可少的牙科干预可以预防并发症,确保在移植恢复期间患者的治疗结果更好.
科学领域:
- 口腔医学是指口腔医学.
- 血液学 血液学 血液学
- 移植手术 移植手术
背景情况:
- 接受血造干细胞移植 (HSCT) 的患者有牙感染的风险.
- 牙上部牙周炎 (AP) 是一种常见的牙感染,可以复杂化HSCT.
- 在这个脆弱人群中,研究根管治疗 (RCT) 的安全性和有效性至关重要.
研究的目的:
- 评估根管治疗 (RCT) 对受感染牙和牙周炎 (AP) 的影响,在接受血造干细胞移植 (HSCT) 的患者中.
- 评估RCT在预防AP恶化,疼痛,胀和细菌血症等并发症方面的安全性和有效性.
主要方法:
- 分析了接受HSCT的100名患者的队列.
- 记录了临床数据,瘤和内牙诊断,以及HSCT类型.
- 在RCT前后监测白细胞/中性粒细胞和C-反应蛋白水平.
主要成果:
- 41%的患者需要RCT,75.6%的患者被诊断为AP,通常有大病变 (45.2%).
- 在54.8%的患者中进行了RCT,没有观察到诸如恶化,疼痛,胀或细菌病等并发症.
- 在RCT后,C-反应蛋白水平下降,表明炎症减少.
结论:
- 根管治疗 (RCT) 是一种安全有效的治疗方法,用于治疗血造干细胞移植 (HSCT) 患者的牙周炎 (AP).
- 强烈建议主动的RCT和勤奋的患者监测,以防止HSCT接受者的内牙感染恶化.
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