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在IBD中准谷氨酸糖二酶II

Diane E Peters1

  • 1Johns Hopkins Drug Discovery, The Johns Hopkins University School of Medicine, Baltimore, MD, United States; Department of Pharmacology and Molecular Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD, United States.

Advances in pharmacology (San Diego, Calif.)
|November 9, 2024
PubMed
概括

谷氨酸碳素酶II (GCPII) 在炎症性肠病 (IBD) 中被上调. GCPII抑制剂在治疗IBD方面表现有前途,像 (S) -IBD3540这样的新型化合物显示出治疗潜力.

关键词:
药物发现 药物发现叶酸化酶1 (FOLH1) 是一种叶酸化酶.谷氨酸甲酸碳二酶II (GCPII) 的使用炎症性肠病 (IBD) 是一种炎症性肠病.在临床前的大肠炎.

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