新抗原架构定义了免疫性,并驱动了异质新抗原表达的瘤的免疫逃避

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Enrich and Expand Rare Antigen-specific T Cells with Magnetic Nanoparticles
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Enrich and Expand Rare Antigen-specific T Cells with Magnetic Nanoparticles

Published on: November 17, 2018

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Malte Roerden1, Andrea B Castro2, Yufei Cui1,3

  • 1Koch Institute for Integrative Cancer Research, Massachusetts Institute for Technology, Cambridge, Massachusetts, USA.

Journal for immunotherapy of cancer
|November 9, 2024
PubMed
概括

瘤抗原表达模式 (NeoAg架构) 决定了免疫逃避和对癌症免疫治疗的抵抗力. 用RNA疫苗和免疫检查点阻塞 (ICB) 向这些模式可以克服异质瘤的耐药性.

关键词:
树突性 树突性 树突性一个T细胞细胞.疫苗 疫苗 疫苗 疫苗

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