透皮内镜与内镜转移性瘤切除术用于瘤性胰腺炎的结果:一种倾向性得分匹配的研究
Ling Ding1, Lei Li1, Jingwen Rao1
1Department of Gastroenterology, Jiangxi Provincial Key Laboratory of Digestive Diseases, Jiangxi Clinical Research Center for Gastroenterology, Digestive Disease Hospital, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China.
概括
透皮内镜性瘤切除术 (PEN) 和内镜性转移性瘤切除术 (ETN) 对瘤性胰腺炎的安全性和疗效相似. 病态患者在现实环境中可能从PEN中获益更多.
科学领域:
- 胃肠病学 胃肠病学
- 最少侵入性的手术
- 关键护理医学 关键护理医学
背景情况:
- 有限的比较研究存在于内镜性切除术用于瘤性胰腺炎 (NP) 的方法.
- 这项研究比较了NP患者的皮肤内镜性瘤切除术 (PEN) 与内镜性转移性瘤切除术 (ETN).
研究的目的:
- 为了比较PEN与ETN在治疗死性胰腺炎的安全性和有效性.
- 在现实世界的临床环境中评估结果.
主要方法:
- 对接受PEN或ETN的成年NP患者进行回顾性队列研究.
- 使用了倾向性得分匹配分析和多变量逻辑回归.
- 两组的安全性和有效性结果进行了比较.
主要成果:
- 分析了280名患者 (142名PEN,138名ETN);基线存在差异.
- 在匹配了91对后,在术后并发症,成功率,复发或重新干预方面没有发现显著差异.
- 多变量分析表明,方法 (PEN与ETN) 与并发症或死亡率之间没有关联.
结论:
- 在死性胰腺炎治疗中,PEN与ETN同样有效和安全.
- 在现实世界中,PEN可能更有效地管理更生病的患者.
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