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Updated: Jun 7, 2025

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梅瓦诺酸途径的抑制通过调节RhoB蛋白稳定性和整体蛋白β1定位来减少膀癌转移

Gang Wang1,2, Tianchen Peng3, Liang Chen3

  • 1Department of Urology, Laboratory of Precision Medicine, Zhongnan Hospital of Wuhan University, Wuhan, China. gangwang.uro@whu.edu.cn.

Communications biology
|November 9, 2024
PubMed
概括

梅瓦诺酸 (MVA) 途径驱动膀癌 (BLCA) 细胞迁移和转移. 抑制这种途径,特别是RhoB的geranylgeranylation,可以降低BLCA细胞的运动性,并提供潜在的治疗策略.

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