在严重的急性肠衰竭的成年人中进行奇米再输液疗法:描述性队列研究
Kirstine Farrer1, Maja Kopczynska1, Maria Barrett1
1National Intestinal Failure Reference Centre, Northern Care Alliance NHS Foundation Trust, University of Manchester, Salford, UK.
JPEN. Journal of parenteral and enteral nutrition
|November 9, 2024
概括
在严重的急性肠衰竭患者中,小麦再输注疗法减少了对肠道营养的需求. 然而,它并没有完全取代肠外营养,也没有显著节省成本.
科学领域:
- 胃肠病学 胃肠病学
- 临床营养学 临床营养学
- 外科手术患者管理
背景情况:
- 在患有高输出囊或口腔的患者中,菌再注射疗法将菌返回到远端肠道.
- 在严重的急性肠衰竭中,菌再输液治疗的有效性仍在研究中.
- 成功的疗法建立被定义为替代腹腔营养的能力.
研究的目的:
- 评价成年患有严重急性肠衰竭的成年患者中菌再输液治疗的有效性.
- 评估菌再输液治疗对亲肠营养需求,药物使用,营养状况,肝功能和治疗成本的影响.
主要方法:
- 进行了一项描述性队列研究.
- 包括患有严重急性肠衰竭的成年患者,原因是高输出口腔或小肠.
- 评估了亲肠道营养需求,药物,营养状况,肝功能和成本.
主要成果:
- 在24名患者中,有15名 (62.5%) 成功建立了菌再输液疗法.
- 腹腔营养需求 (体积,能量,) 显著减少 (P=0.002).
- 37.5%的患者无法耐受治疗;只有8.3%的患者完全停止了对肠道营养. 相关成本为每名患者每天40.27美元.
结论:
- 梅再输液疗法可以减少对肠道治疗和药物治疗的需要.
- 在患有严重急性肠衰竭的患者中,该疗法并未完全取代肠外营养.
- 没有观察到菌再输注疗法显著节省成本.
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