在致癌,癌症治疗和抵抗机制中的RAS信号

Xiaojuan Yang1, Hong Wu2,3

  • 1Liver Digital Transformation Research Laboratory, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Chengdu, Sichuan, 610041, P.R. China.

PubMed
概括

RAS突变在癌症中很常见,并且与糟糕的结果有关. 最近针对KRAS的疗法,如KRASG12C抑制剂,提供了新的希望,目前正在对其他RAS变体和抗药机制进行研究.

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