病理性痕的症状是否与神经功能或密度有关? 一个范围审查审查
M De Henau1, S Schins2, C Colla3
1Department of Plastic and Reconstructive Surgery, Maastricht University Medical Center, Maastricht, P Debyelaan 25, 6229 HX Maastricht, The Netherlands; GROW school for Oncology and Reproduction, Maastricht University, Universiteitssingel 40, 6229 ER Maastricht, the Netherlands.
Burns : journal of the International Society for Burn Injuries
|November 10, 2024
概括
病理性痕 (PS) 可能涉及神经功能障碍,由皮肤感觉和密度的改变表明. 神经性炎症可能导致PS的发展和症状,尽管需要更多的研究.
科学领域:
- 皮肤病学 皮肤病学
- 神经学 神经学
- 病理学 病理学 病理学
背景情况:
- 过度缩性痕和状痕是病理性痕 (PS),会引起疼痛和.
- 神经功能,密度和PS症状之间的关系尚不清楚.
研究的目的:
- 审查目前关于神经功能和PS中的密度的知识.
- 探索感官变化,神经密度和PS症状之间的关联.
主要方法:
- 进行了范围审查.
- 在PubMed,Embase和Web-of-Science进行了系统的搜索.
- 相关研究被两个独立审稿人选择和分析.
主要成果:
- 审查中包括了19项研究.
- 在PS中,敏感性似乎受到了干扰,具有增加的全音和改变的热感知值,表明小纤维神经病变.
- 神经纤维密度不同,限制了直接比较,但神经可能在PS形成和症状中发挥作用.
结论:
- 研究之间存在显著的异质性,防止得出坚定的结论.
- 有证据表明,皮肤神经系统通过神经性炎症参与PS病理生理学和症状.
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