4岁以后的补丁对患有单侧先天性白内障的儿童有好处吗?
Carolyn D Drews-Botsch1, George Cotsonis2, Marianne Celano3
1Department of Global and Community Health, College of Public Health, George Mason University, Fairfax, Virginia.
Ophthalmology
|November 10, 2024
概括
在患有单边先天性白内障的儿童中,早期视力敏度测试可靠地预测长期结果. 一旦达到可靠的敏度,可以调整或停止贴片治疗,特别是对于视力较差的人来说.
科学领域:
- 眼科医生 眼科 眼科
- 儿科医学 儿科医学
- 视觉科学 视觉科学 视觉科学
背景情况:
- 单侧先天性白内障需要及时干预,通常涉及封闭疗法 (补丁).
- 确定补丁的最佳持续时间对于视觉发育和最小化潜在的负面影响至关重要.
- 对长期视觉结果的可靠预测有助于治疗决策.
研究的目的:
- 评估早期光型敏度测量在患有单边先天性白内障的儿童中的可靠性和预测价值.
- 提供证据,以指导关于继续或停止封闭治疗的决定.
- 评估早期补丁持续时间和最终视力敏度之间的关系.
主要方法:
- 一个队列设计使用婴儿阿法基亚治疗研究 (IATS) 的数据.
- 包括105名没有视力威胁不良事件的儿童.
- 评估了10.5岁视力敏度 (VA) 与48至60个月龄之间报告的修补小时之间的相关性.
主要成果:
- 在4岁时的视敏度测量可靠 (ICC=0.83) 和在10.5岁时预测VA (r=0.83,P<0.01).
- 在38%的儿童中,VA在10.5岁时非常接近4岁时的测量.
- 在4岁至5岁之间修补的数量与VA的变化无关.
结论:
- 早期的视型敏度测量 (大约4岁) 是对患有单边先天性白内障的儿童最终视觉结果的可靠预测器.
- 一旦获得可靠的敏度,可以考虑停止或减少补丁,特别是在视力较差的儿童中.
- 在停止闭塞治疗之前,应考虑诸如潜伏性阴影,生活质量和双眼功能等因素.
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