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新出现的证据表明,孕前的类固醇疗法适用于酒精使用障碍

A Leslie Morrow1, Minna H McFarland2, Todd K O'Buckley3

  • 1Department of Psychiatry, University of North Carolina at Chapel Hill, School of Medicine, Chapel Hill, NC, United States; Department of Pharmacology, University of North Carolina at Chapel Hill, School of Medicine, Chapel Hill, NC, United States; Bowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, School of Medicine, Chapel Hill, NC, United States.

International review of neurobiology
|November 10, 2024
PubMed
概括

神经活性孕妇类固醇显示出治疗酒精使用障碍 (AUD) 的前景. 研究审查了临床前和临床证据,神经生物学,以及开发这些类固醇疗法以缓解AUD的挑战.

关键词:
孕诺 (Allopregnanolone) 是一种含有甲基的药物.皮质营养素释放因子 (CRF)多巴胺的传输方式激发性/抑制性 (E/I) 的平衡.炎症 炎症是一种炎症.这是一种神经类固醇.孕产妇使用的孕.

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