双胞胎缺血症和慢性阻塞性肺病的严重程度之间的关联:一个横截面研究
Horacio Matias Castro1, Joaquin Maritano Furcada1, Eduardo Luis De Vito2
1Pulmonology Department, Hospital Italiano de Buenos Aires, Argentina.
概括
严重的慢性阻塞性肺部疾病 (COPD) 与较高的阴性腺的患病率有关. 这项研究发现,严重的慢性肺炎是男性阴高性恋症的独立危险因素.
科学领域:
- 肺部病理学 肺部病理学
- 内分泌学 在内分泌学.
- 男人的健康 男人的健康
背景情况:
- 慢性阻塞性肺部疾病 (COPD) 经常与诸如阴性双胞胎症等并发症同时发生.
- 需要进一步澄清COPD严重程度和阴性腺体缺陷症之间的关系.
研究的目的:
- 为了调查COPD严重程度和阴性腺体缺陷症之间的关联.
- 为了比较低体与高体COPD患者的临床特征.
主要方法:
- 对患有稳定COPD的男性进行横截面研究.
- 通过症状 (老年男性雄激素缺陷调查问卷) 和低 (<300ng/dL) 诊断的阴性双症.
- 使用西班牙COPD指南风险标准对COPD严重程度进行分类;使用多变量逻辑回归.
主要成果:
- 严重的慢性肺炎 (1.8倍) 与轻度的慢性肺炎 (p=0.007) 相比,低性腺体的患病率显著更高.
- 严重的慢性肺炎独立增加了阴性腺体缺陷的几率 (OR 2.60,p=0.012),根据年龄,BMI,CVD和CRF进行调整.
- 阴阴性慢性肺炎患者的FVC和FEV1减少,呼吸障碍增加.
结论:
- 严重的慢性肺炎与较高的阴道腺的患病率有关.
- 严重的COPD是催眠症的独立风险因素.
- 推对COPD患者,特别是那些患有严重疾病的患者进行催性腺体的评估.
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