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Updated: Jun 7, 2025

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了解和测量瘤流层中的机械信号

Fàtima de la Jara Ortiz1, Chiara Cimmino2,3, Maurizio Ventre2,3,4

  • 1Department of Medical BioSciences, Radboud University Medical Center, Nijmegen, The Netherlands.

FEBS open bio
|November 11, 2024
PubMed
概括

瘤的微环境 瘤的微环境

关键词:
与癌症相关的纤维细胞.细胞外矩阵是细胞外矩阵.机械生物学 机械生物学硬性 硬性 硬性瘤机械学的机制

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The Tumor Microenvironment02:17

The Tumor Microenvironment

Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
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