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Updated: Jun 7, 2025

Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform
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一个基于贝叶斯动态模型的适应性设计,用于在I/II期临床试验中的瘤学剂量优化

Yingjie Qiu1,2, Mingyue Li1

  • 1Peter O'Donnell Jr. School of Public Health, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

Pharmaceutical statistics
|November 11, 2024
PubMed
概括

项目Optimus旨在改革化疗剂量. 本研究介绍了瘤学试验的贝叶斯适应性设计,将毒性和疗效结合起来,以确定最佳剂量 (OD) 并改善药物开发.

关键词:
贝叶斯的方法 贝叶斯的方法第I/II阶段试验试验适应性设计是适应性的设计.延迟的结果延迟的结果模型选择,模型选择.最佳的剂量是最优的剂量.

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