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Updated: Jun 7, 2025

Real-Time Fluorescent Measurement of Synaptic Functions in Models of Amyotrophic Lateral Sclerosis
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Published on: July 16, 2021

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[在SOD-1相关的肌缩侧面硬化症中托弗森的当前景观]

Taro Ishiguro1, Tetsuya Nagata, Takanori Yokota

  • 1Department of Neurology and Neurological Science, Institute of Science Tokyo.

Brain and nerve = Shinkei kenkyu no shinpo
|November 11, 2024
PubMed
概括

托弗森是一种针对SOD1家族性肌缩侧面硬化症 (ALS) 的基因特异性疗法,现在已在美国和欧盟获得批准. 目前正在进行的评估将确定其完整的安全性和有效性.

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Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
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