建立腹膜透析技术生存核心结果衡量标准:脏病学-腹膜透析的标准化结果共识研讨会报告
Emma H Elphick1, Karine E Manera2,3, Andrea K Viecelli4,5,6,7
1School of Medicine, School of Primary, Community and Social Care, Keele University, Keele, Staffordshire, UK.
概括
腹膜透析技术的生存定义有很大的不同. 一个国际共识研讨会建议重新定义这个结果为"转移到血液透析",以便在临床试验中提供更清晰,标准化的报告.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 临床试验方法论 临床试验方法论
- 患者报告的结果
背景情况:
- 腹腔透析 (PD) 技术的生存是患者,护理人员和临床医生的关键结果.
- 目前的PD技术生存的定义和报告缺乏标准化,阻碍了结果的比较.
- 现有的术语,例如:
- 技术失败失败的技术失败的技术
- 带有负面内涵. 有负面内涵.
研究的目的:
- 建立一个标准化,核心结果衡量腹透析技术生存的标准.
- 为报告PD技术生存而开发中立和可行的术语.
- 为了解决定义和测量PD技术生存率的异质性.
主要方法:
- 进行了一场国际共识研讨会,涉及患者,护理人员和卫生专业人员.
- 通过视频会议促进了讨论,并根据主题进行了分析.
- 核心事件定义和命名是通过合作开发的.
主要成果:
- 来自13个国家的55名参与者为共识做出了贡献.
- 关键主题包括捕捉结果方面,采用中立的命名法,并确保可行性.
- 建议的核心结果措施被重新定义为"转移到血液透析".
结论:
- 在腹腔透析中技术生存的核心结果应该重新定义为"转移到血液透析".
- 建议实施标准化,中立的术语,并专注于永久性事件.
- 记录转移原因对于全面报告至关重要.
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