纳秒脉冲驱动氧气泡等离子激活低度酒精溶液及其杀菌机制
YiQian Li1, Ke Song2, YanZhao Ning1
1School of Electrical and Electronic Engineering, Huazhong University of Science and Technology, Wuhan, Hubei 430074, P.R. China.
ACS omega
|November 11, 2024
概括
血激活乙醇溶液为高度酒精消毒剂提供了更安全,更有效的替代品. 氧气泡等离子激活乙醇溶液 (PAES) 使用低度乙醇实现了完全的细菌消除,确定过氧酸作为关键杀菌剂.
科学领域:
- 血科学是一门科学课.
- 微生物学 微生物学
- 化学工程是化学工程的重要组成部分.
背景情况:
- 高度酒精消毒剂 (70-75%) 具有易燃性和气味等风险.
- 需要更安全,同样有效的绝育方法.
研究的目的:
- 为了研究纳米秒脉冲驱动泡泡排放激活的低度乙醇溶液的灭菌效率.
- 确定促进激活血乙醇溶液 (PAES) 抗菌活性的主要因素.
主要方法:
- 细菌样本暴露于氧气泡等离子激活乙醇溶液 (PAES) 和与空气PAES和等离子激活水 (PAW) 的比较.
- 在PAES中使用测试套件和GC-MS分析无机反应物种和有机分解产物.
- 在不同温度 (4°C和-20°C) 储存后对杀菌作用的评估.
主要成果:
- 10%乙醇PAES表现出优异的灭菌能力,在3分钟内减少了7个数量级的细菌数量,能量输入低 (10.9 J/ml).
- 过氧酸 (CH3COOOH) 被确定为PAES的主要杀菌因子.
- 在-20°C保存的PAES可保持4天的细菌完全消除.
结论:
- 血活性乙醇溶液 (PAES) 为传统高度酒精消毒剂提供了一个有希望的,更安全的替代品.
- PAES的有效性与产生反应性物种,特别是过氧酸的产生有关.
- 优化的储存条件,如-20°C,可以保持PAES强大的杀菌特性.
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