在瑞典的开角眼中失明的发生率:长期随访研究
Curt Ekström1, Christoffer Carlsson1
1Department of Surgical Sciences, Ophthalmology, Uppsala University, Uppsala, Sweden.
Upsala journal of medical sciences
|November 11, 2024
概括
开角玻璃眼 (OAG) 可以导致不可逆转的失明. 这项研究发现,大约9.3%的OAG患者患有双侧失明,年龄较大和男性性别是关键风险因素.
科学领域:
- 眼科医生 眼科 眼科
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 在全球范围内,开角光眼 (OAG) 是不可逆转的视力丧失的主要原因.
- 有限的前性数据存在于OAG患者发展双边失明的风险.
研究的目的:
- 调查新诊断的开角玻璃眼患者双侧失明的发病率和风险因素.
- 为了解OAG.的长期视觉预后提供关键数据.
主要方法:
- 分析了来自瑞典 (1979-2006) 的354名新诊断的OAG患者队列.
- 使用世界卫生组织失明标准审查了医疗记录和视野.
- 使用发病率,标准化发病率 (SMR) 和Cox比例危险模型来评估风险因素.
主要成果:
- 截至2023年8月,双边失明的总体发病率比例为9.3%.
- 在前20年内,发生率比例为8.2%.
- 男性性别 (SMR 2.33) 和年龄增长 (每5年危险比率翻一番) 是导致失明的重要危险因素.
结论:
- 大约十分之一的新诊断OAG的患者患有双边失明.
- 老年和男性性别被确定为OAG患者失明的重要预测因素.
- 研究结果强调了早期检测和管理的重要性,以防止OAG的视力丧失.
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