关于传染性角质炎的临床微生物学概况和治疗结果的研究
Abhay Lune1, Supriya Pokle1, Ozukhil Radhakrishnan2
1Ophthalmology, Dr. D.Y. Patil Medical College, Hospital and Research Centre, Pimpri, IND.
Cureus
|November 11, 2024
概括
传染性角膜炎 (IK) 是导致失明的主要原因. 真菌感染是最常见的,但医疗治疗在两个月内治愈了大多数.
科学领域:
- 眼科医生 眼科 眼科
- 微生物学 微生物学
背景情况:
- 传染性角膜炎 (IK) 是全球角膜失明的主要原因.
- 细菌,真菌,病毒和原生动物感染可以导致IK,可能导致角膜穿孔.
研究的目的:
- 确定传染性角质炎的临床和微生物特征.
- 评估感染性角膜炎患者的治疗结果.
主要方法:
- 在印度马哈拉施特拉州西部的107名IK患者 (≥15年) 的前性观察性研究.
- 用于微生物学检查的角膜除 (格拉姆染色,培养).
- 医疗或手术管理,在随访期间评估结果.
主要成果:
- 在培养物中,真菌分离物 (57%) 是最常见的;Fusarium物种占主导地位.
- 葡萄球菌是最常见的格拉姆阳性生物体;Pseudomonas aeruginosa是唯一的格拉姆阴性细菌.
- 96%的医疗治疗在两个月内愈合;严重/中度需要穿透式角质塑性.
结论:
- 在本研究群体中,真菌分离物是最常见的IK病因.
- 对大多数IK病例而言,医疗管理是有效的,并观察到快速愈合.
- 严重病例需要进行外科手术,移植的存活率很高,但存在排斥和内眼炎的风险.
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