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Published on: October 14, 2014
在SpaceOAR Vue水凝程序期间发生过敏性休克
Lauren Nesi1, Paramjot Gogia1,2, Aishwarya Navalpakam3
1Department of Urology, Detroit Medical Center, 4160 John R St., Harper Professional Building, Suite 1021, Detroit, MI, 48201, United States.
在SpaceOAR Vue的前列腺癌放射治疗过程中发生了一种罕见的过敏性休克和心脏骤停病例. 本报告强调了直肠水凝间隔器的潜在原因和临床考虑.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 辐射瘤学 辐射瘤学
- 麻醉学 麻醉学
背景情况:
- 太空OAR Vue水凝用于在外部束辐射疗法 (EBRT) 期间在前列腺和直肠之间创造空间.
- 过敏反应是一种对医疗程序和物质的罕见但严重的不良反应.
- 包括EBRT在内的前列腺癌治疗需要仔细管理潜在的并发症.
研究的目的:
- 报告在SpaceOAR Vue水凝放置期间发生的第一个手术内过敏性休克和心脏骤停的泌尿病例.
- 讨论这种不良反应的潜在致病因子.
- 为医疗保健提供者使用直肠水凝间隔器提供临床考虑.
主要方法:
- 一个70岁的男性患者的病例报告,因为晚期局部性前列腺癌而接受EBRT.
- 在SpaceOAR Vue水凝安置期间发生了导致心脏骤停的手术内过敏性休克事件的记录.
- 审查潜在的促成因素,包括水凝成分,外科手术期间的抗生素和局部麻醉.
主要成果:
- 观察到一种独特而罕见的手术内过敏性休克和心脏骤停的情况.
- 该事件发生在SpaceOAR Vue水凝间隔器放置期间.
- 确定的可能的促成因素包括水凝中的聚乙烯糖醇 (PEG) 和,外科期间的抗生素和局部利多卡因麻醉剂.
结论:
- 临床医生应该意识到在SpaceOAR Vue水凝手术期间可能出现严重的过敏反应.
- 对水凝和相关药物的特定成分进行进一步调查可能是有必要的.
- 实施相关考虑对于在直肠水凝间隔剂施用期间的患者安全至关重要.
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