Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Vaccinations01:51

Vaccinations

44.1K
Overview
44.1K
Cross-reactivity00:42

Cross-reactivity

31.0K
Overview
31.0K
Mutation, Gene Flow, and Genetic Drift01:09

Mutation, Gene Flow, and Genetic Drift

58.1K
In a population that is not at Hardy-Weinberg equilibrium, the frequency of alleles changes over time. Therefore, any deviations from the five conditions of Hardy-Weinberg equilibrium can alter the genetic variation of a given population. Conditions that change the genetic variability of a population include mutations, natural selection, non-random mating, gene flow, and genetic drift (small population size).
58.1K
Gene Flow02:39

Gene Flow

34.8K
Gene flow is the transfer of genes among populations, resulting from either the dispersal of gametes or from the migration of individuals.
34.8K
Genetic Drift03:33

Genetic Drift

39.5K
Natural selection—probably the most well-known evolutionary mechanism—increases the prevalence of traits that enhance survival and reproduction. However, evolution does not merely propagate favorable traits, nor does it always benefit populations.
39.5K
Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

1
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
1

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Exploring the Potential of Calebin-A in Targeting Obesity-Related Genes and Pathways.

Journal of cellular and molecular medicine·2026
Same author

Superoxide Dismutase-Centered Modulation by Curcumin in Cardiovascular Diseases: Mechanistic Insights and Translational Implications.

Journal of cellular and molecular medicine·2026
Same author

Effects of trehalose supplementation on bone healing, physical function, and pain in patients with pertrochanteric fractures: a randomized controlled trial.

Scientific reports·2026
Same author

Identification of Genetic Determinants of Weight Loss Efficacy After Roux-en-Y Gastric Bypass Surgery.

Bariatric surgical practice and patient care·2026
Same author

Promising Anti-Cancer Effects and Mechanisms of Baicalin and Baicalein in the Treatment of Oral Cancer: A Comprehensive Review.

Oral diseases·2026
Same author

Evaluating the Effects of Nanocurcumin Supplementation in Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Endocrinology, diabetes & metabolism·2026

相关实验视频

Updated: Jun 7, 2025

Determination of Vaccine Immunogenicity Using Bovine Monocyte-Derived Dendritic Cells
12:54

Determination of Vaccine Immunogenicity Using Bovine Monocyte-Derived Dendritic Cells

Published on: May 19, 2023

1.8K

地理多样性如何影响疫苗的有效性?

Mohammad Abavisani1, Bahareh Ansari2, Negar Ebadpour2

  • 1Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran.

Clinical and experimental vaccine research
|November 11, 2024
PubMed
概括

由于宿主因素,营养和环境的变化,地理位置显著影响疫苗的疗效. 根据当地情况调整疫苗接种策略可以改善免疫反应并减少健康差异.

关键词:
地理 地理 地理 地理.豁免权是一种豁免权.免疫学因素 免疫学因素医疗 医疗 医疗 医疗疫苗 疫苗是一种疫苗.

更多相关视频

Use of an Influenza Antigen Microarray to Measure the Breadth of Serum Antibodies Across Virus Subtypes
08:52

Use of an Influenza Antigen Microarray to Measure the Breadth of Serum Antibodies Across Virus Subtypes

Published on: July 26, 2019

8.1K
Author Spotlight: A Pseudotype Virus System for Assessing Omicron Subvariants and Neutralizing Antibodies in SARS-CoV-2 Research
06:08

Author Spotlight: A Pseudotype Virus System for Assessing Omicron Subvariants and Neutralizing Antibodies in SARS-CoV-2 Research

Published on: September 8, 2023

1.1K

相关实验视频

Last Updated: Jun 7, 2025

Determination of Vaccine Immunogenicity Using Bovine Monocyte-Derived Dendritic Cells
12:54

Determination of Vaccine Immunogenicity Using Bovine Monocyte-Derived Dendritic Cells

Published on: May 19, 2023

1.8K
Use of an Influenza Antigen Microarray to Measure the Breadth of Serum Antibodies Across Virus Subtypes
08:52

Use of an Influenza Antigen Microarray to Measure the Breadth of Serum Antibodies Across Virus Subtypes

Published on: July 26, 2019

8.1K
Author Spotlight: A Pseudotype Virus System for Assessing Omicron Subvariants and Neutralizing Antibodies in SARS-CoV-2 Research
06:08

Author Spotlight: A Pseudotype Virus System for Assessing Omicron Subvariants and Neutralizing Antibodies in SARS-CoV-2 Research

Published on: September 8, 2023

1.1K

科学领域:

  • 免疫学 免疫学 免疫学
  • 公共卫生 公共卫生
  • 疫苗学 疫苗学 疫苗学

背景情况:

  • 疫苗接种对全球健康至关重要,但疫苗有效性和免疫性越来越多地存在地理差异.
  • 这些变异表明宿主免疫和各种环境,遗传和营养因素之间的复杂相互作用.
  • 了解这些差异对于优化全球疫苗接种战略至关重要.

研究的目的:

  • 探索疫苗有效性的地理差异背后的多因素原因.
  • 为了确定影响整个人群接种疫苗反应的关键宿主,环境和生活方式因素.

主要方法:

  • 这次审查综合了关于疫苗疗效地理差异的现有研究.
  • 分析的关键因素包括宿主特征,营养状况,生活方式和生态影响.

主要成果:

  • 主体因素如年龄,肥胖,性别和遗传多样性 (特别是MHC) 显著影响疫苗的有效性.
  • 微量营养素缺乏 (维生素,),压力,睡眠,酒精和体力活动极大地影响了疫苗诱导的免疫力.
  • 肠道微生物群和环境污染物也会影响免疫系统对疫苗接种的反应.

结论:

  • 疫苗有效性的地理差异是由宿主,环境和生活方式因素的复杂相互作用驱动的.
  • 根据特定的地理和社会背景调整疫苗接种策略对于提高疫苗的有效性至关重要.
  • 个性化方法可以帮助减少疫苗反应差异,并加强传染病控制工作.