由于肺动脉静脉形缺陷而导致的缺血性中风:系统性审查
Srinath Ramaswamy1, Izabela Marczak2, Yohannes Mulatu2
1Columbia University Medical Center, New York, USA.
Brain circulation
|November 11, 2024
概括
肺动脉静脉形形 (PAVMs) 可以导致年轻人的中风,通常会影响多个大脑区域. 在中风患者中早期查PAVMs对于预防复发事件至关重要.
科学领域:
- 神经学 神经学
- 血管医学 血管医学
- 放射学 放射学是一门学科.
背景情况:
- 肺动脉静脉形形 (PAVMs) 是通过悖论性栓塞引起急性缺血性中风 (AISs) 的已知原因之一.
- 与PAVM相关的AIS的临床和成像特征还没有得到很好的描述.
- 了解这些特征对于及时诊断和预防中风至关重要.
研究的目的:
- 系统地审查由于PAVMs而经历AIS的患者的临床和成像特征.
- 确定可能有助于查AIS患者的PAVMs的关键特征.
- 为预防复发性中风提供适当的治疗策略.
主要方法:
- 在MEDLINE,EMBASE和Web of Science数据库中进行系统的文献搜索,截至2023年10月.
- 包括所有年龄段的患者与PAVM归因于AIS,不包括没有临床数据的研究.
- 数据提取包括人口统计,AIS特征 (位置,领土) 和PAVM特征 (位置,大小,处理).
主要成果:
- 一个47岁的女性患有小脑AIS和右下叶PAVM的病例,接受了卷轴闭合治疗.
- 对102名患者的分析显示,平均年龄为47.4岁,其中67%为女性.
- 常见的AIS影响前部循环 (50%) 和后部循环 (37%);PAVMs通常是单个 (78%) 和下叶 (66%).
- 在33%的患者中存在遗传性出血端膜切除症 (HHT).
结论:
- 与PAVM相关的中风往往发生在年轻人身上.
- 这些中风表现出多焦点呈现和后部循环干扰的倾向.
- 对于患有PAVMs和AIS的患者,建议对HHT和静脉血栓进行查.
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