在荷兰的移民和社会经济群体中,胃癌风险高
Duco T Mülder1, Hilliene J van de Schootbrugge-Vandermeer1, James F O'Mahony1,2
1Department of Public Health, Erasmus Medical Center, Rotterdam, the Netherlands.
概括
一些来自波斯尼亚-黑塞哥维那,土耳其和中国的第一代移民面临更高的胃癌风险. 针对性查和预防策略对于这些低发病率国家的高风险群体至关重要.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 在瘤学瘤学.
背景情况:
- 在不同的人群中,胃癌风险在不同的人群中存在很大差异.
- 针对性查对于早期检测至关重要,尤其是在发病率低的地区.
- 移民和社会经济地位 (SES) 是胃癌风险的潜在决定因素.
研究的目的:
- 为了确定荷兰胃癌的高风险群体.
- 调查移民史和SES对胃癌发病率的影响.
- 为了告知有针对性的胃癌预防战略.
主要方法:
- 使用来自荷兰癌症登记处 (2010-2022) 的数据进行了回顾性队列研究.
- 移民人口和本地出生人口之间的胃癌发病率的比较.
- 根据出生地计算的赔率比率 (OR),控制年龄,性别和SES;对第二代移民和SES影响的分析.
主要成果:
- 来自波斯尼亚和黑塞哥维那 (OR,2.42),土耳其 (OR,2.22) 和中国 (OR,1.92) 的第一代移民的胃癌风险明显更高.
- 低SES与增加胃癌的几率有关.
- 即使在调整了SES后,第一代移民仍然存在高风险;第二代移民没有显示出明显更高的风险.
结论:
- 特定的第一代移民群体在荷兰保持胃癌风险较高.
- 识别这些高风险人群是实施有针对性的胃癌预防计划的关键.
- 建议初级保健医生对有针对性的Helicobacter pylori查和早期检测进行进一步的研究.
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