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Updated: Jun 7, 2025

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
00:06

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila

Published on: August 20, 2019

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通过调节 WDR5 稳定性,E3 泛素酶 RNF220 维持后脑Hox 表达模式

Huishan Wang1, Xingyan Liu2,3, Yamin Liu1,4

  • 1Key Laboratory of Genetic Evolution and Animal Models, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China.

eLife
|November 11, 2024
PubMed
概括

RNF220 E3 泛素酶调节霍克斯基因表达和后脑发育. 丢失RNF220导致去抑制的Hox基因,影响pontein核和神经回路,由WDR5.5介导.

关键词:
霍克斯·霍克斯 (Hox Hox) 是一个骗子.在RNF22020中,我们可以使用RNF220这是WDR5的WDR5.发育生物学是发展生物学.这里是鼠标鼠标鼠标鼠标鼠标鼠标.庞丁核中的核.

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