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载体动态支欧洲目前和未来的传播病毒的出现

Marine J Petit¹, Nicholas Johnson^1,2, Karen L Mansfield²

¹Faculty of Health and Medical Sciences, University of Surrey, Guildford GU2 7XH, UK.

The Journal of general virology

|November 11, 2024

概括

像TBEV和CCHFV这样的传播疾病在欧洲正在增加. 本综述探讨了生态,气候变化和抗病毒反应,以了解和减轻这些威胁.

科学领域:

* 兽医昆虫学和病毒学
* 公共卫生和流行病学

背景情况:

*传播的疾病 (TBD) 是欧洲人类和动物健康的重大和日益增长的威胁.
* 传播脑炎病毒 (TBEV) 和克里米亚 - 刚果出血热病毒 (CCHFV) 是主要的新兴问题,分别由Ixodes ricinus和Hyalomma marginatum传播.
*是高效的载体,因为它们能够将病原体传递给多个宿主,并在整个生命周期中保持感染,但它们的生态和载体能力的关键方面需要进一步研究.

研究的目的:

* 审查和综合当前对影响欧洲的矢量能力因素的知识.
* 为了研究气候变化对和TBD生态的影响,使用TBEV和CCHFV作为具体例子.
* 分析的内在抗病毒反应在确定其传播病毒的能力方面的作用.

主要方法:

* 关于生态学,欧洲的TBD,气候变化影响和抗病毒机制的科学出版物的综合文献综述.
*案例研究分析,重点关注TBEV和CCHFV传播动态和生态因素.
*整合了关于载体生物学,病原体传播和环境影响的数据.

主要成果:

* 气候变化被确定为改变分布,活动模式和TBD流行病学的重要驱动因素.
*的天生的免疫系统,特别是它的抗病毒反应,在调节病原体的复制和传播方面发挥着至关重要的作用.
*了解环境因素,生物和宿主-病原体相互作用之间的相互作用对于评估TBD风险至关重要.

结论:

*对的载体能力有全面的了解,受气候和内在免疫的影响,对于有效的TBD控制至关重要.
*这些发现支持应用"一个健康"框架,制定整合策略,减轻欧洲的TBD.
*需要对-病原体-环境相互作用进行进一步的研究,以预测和管理TBDs带来的未来公共卫生挑战.

关键词:

气候变化气候变化气候变化新兴病毒是新出现的病毒.的免疫力的免疫力传播疾病传播疾病矢量能力能力矢量能力矢量能力

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