儿童的喘和记忆功能
Nicholas J Christopher-Hayes1,2, Sarah C Haynes3, Nicholas J Kenyon4
1Center for Mind and Brain, University of California, Davis.
JAMA network open
|November 11, 2024
概括
儿童喘与儿童的记忆力缺陷有关. 早期发作的喘可能会使记忆障碍恶化,并影响注意力和处理速度等执行功能.
科学领域:
- 儿科健康 儿科健康
- 神经科学是一个神经科学.
- 呼吸系统医学 呼吸系统医学
背景情况:
- 喘是儿童常见的慢性呼吸道疾病,在美国影响了数百万人.
- 虽然动物模型表明喘可能导致记忆缺陷,但它对儿童记忆发展的影响尚不清楚.
研究的目的:
- 研究儿童喘与儿童的认知能力,特别是记忆能力之间的关联.
- 确定喘发病时间是否会影响记忆发育和执行功能.
主要方法:
- 一项使用青少年大脑认知发展 (ABCD) 研究数据的纵向队列研究.
- 包括大约11800名9-10岁的儿童,随访时间超过两年.
- 分析了父母报告的喘状况 (早期发病,晚发病或没有病史) 和认知结果之间的关联,包括情节性记忆,处理速度和执行功能.
主要成果:
- 与对照组相比,早期出现喘的儿童在记忆方面表现出较慢的纵向改善.
- 在横截面分析中,患有喘的儿童在情节性记忆,处理速度和抑制/注意力任务方面得分较低.
- 这些认知缺陷在多个领域被观察到,包括记忆和执行功能.
结论:
- 儿童喘与儿童记忆能力受损有关.
- 记忆障碍的严重程度可能会更大,如果喘发作较早.
- 喘也可能对执行功能产生负面影响,例如处理速度和注意力.
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