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在IBD小鼠模型中,双重作用的tofacitinib载入的PLGA纳米颗粒减轻了结肠炎

Nidhi Seegobin1, Laura E McCoubrey1,2, Cécile Vignal3

  • 1Department of Pharmaceutics, UCL School of Pharmacy, University College London, WC1N 1AX, 29-39 Brunswick Square, London, UK.

Drug delivery and translational research
|November 11, 2024
PubMed
概括

装有托法西替尼酸盐 (TFC) 的新纳米颗粒为炎症性肠病 (IBD) 提供了有前途的治疗方法. 这种有针对性的输送通过将药物集中在肠道中来减少副作用,从而改善治疗结果.

关键词:
结肠药物输送和向的目标.炎症性肠病是一种炎症性肠病.微生物组医学是微生物组医学.急性结肠炎的小鼠模型纳米颗粒 纳米颗粒纳米沉是一种纳米沉.在 PLGA PLGA 中.托法西提尼布 (tofacitinib) 是一种可怕的药物.

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