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Updated: Jun 7, 2025

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转录后控制驱动光激酶 在人类癌症中的表达

Roberta Cacioppo1, Deniz Rad1, Giulia Pagani2

  • 1Department of Pharmacology, University of Cambridge, Cambridge, United Kingdom.

PloS one
|November 11, 2024
PubMed
概括

极光激酶A (AURKA) 表达在癌症中通常因转录后控制而失调. 这项研究表明,microRNA let-7a和替代多基化会影响AURKA水平,导致各种癌症的mRNA和蛋白质表达不一致.

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