在结合轨道减压和葡萄糖皮质体治疗后眼内压力变化对于Graves轨道病变的治疗
Mingyang Wang1, Dongmei Li1,2
1Department of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing.
The Journal of craniofacial surgery
|November 11, 2024
概括
在轨道减压之前的抛物线糖皮质类药物有效地降低了Graves轨道病变 (GO) 的眼内压力 (IOP). 对于活跃的GO来说,这种治疗可能是最好的,以降低内腔压力,特别是在向上的视线上.
科学领域:
- 眼科医生 眼科 眼科
- 内分泌学 在内分泌学.
背景情况:
- 格雷夫斯轨道病 (GO) 可能导致眼内压力 (IOP) 升高.
- 轨道减压 (OD) 是GO的一种手术选择.
- 葡萄糖皮质类药物 (GCs) 在GO管理中使用.
研究的目的:
- 评估带有或没有葡萄糖皮质体 (GCs) 的轨道减压 (OD) 对Graves轨道病变 (GO) 患者眼内压力 (IOP) 的影响.
主要方法:
- 从76名GO患者的99个轨道的回顾性审查.
- 患者接受了单独的OD (A组),OD与静脉注射GC (B组) 或抛物线GC (C组).
- 在手术前和手术后的IOP测量是在初级和向上视线上进行的.
主要成果:
- 在A组和C组中,初级目光中的中位术后内血压下降.
- 上方视线的IOP始终高于主要视线的IOP.
- 抛物线GCs (C组) 显著降低了向上视线IOP,接近主要视线IOP.
结论:
- 在OD之前的Parabulbar GC治疗有效地降低了GO患者的初级和向上视力IOP.
- 这种方法可能有利于GO的活跃或充血阶段的患者.
- 抛物线GC可以导致手术后更大程度的降低向上视力IOP.
相关概念视频
Open Angle Glaucoma: Treatment
393
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
393
Glaucoma: Overview
508
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
508
Angle Closure Glaucoma: Treatment
438
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
438
Accessory Structures of the Eye
1.5K
Optical perception, or vision, is an extraordinary sense dependent on converting light signals received via the ocular organs. These organs, known as eyes, are securely positioned within the bony cavities of the skull, called orbits. The orbits serve a dual purpose: a protective shield for the ocular globes and a stable attachment point for the soft ocular tissues. The eye's external protective mechanisms include the eyelids, which are edged with lashes that act as a barrier against foreign...
1.5K


