区分Providencia物种的血液感染:基于人口的分析分析
Felicity Edwards1, Kristin H Edwards2, Alexis Tabah3
1Queensland University of Technology (QUT), Brisbane, Queensland, Australia.
Diagnostic microbiology and infectious disease
|November 11, 2024
概括
普罗维迪纳斯物种会导致血流感染 (BSI),特别是在老年男性身上. 虽然发病率相似,但Providencia stuartii和Providencia rettgeri BSIs在患者的因素和结果上有所不同,P. rettgeri的死亡率更高.
科学领域:
- 传染性疾病 传染性疾病
- 流行病学 流行病学
- 微生物学 微生物学
背景情况:
- 普罗维迪安西亚物种是已知的血液感染 (BSI) 的原因.
- 由于不经常发生,Providencia物种BSI的流行病学定义不清楚.
- 这项研究旨在确定Providencia物种BSI.的发病率,决定因素和结果.
研究的目的:
- 确定澳大利亚昆士兰州Providencia物种BSI的总体发病率.
- 确定与Providencia物种BSI.相关的决定因素和结果.
- 将P. stuartii和P. rettgeri BSI的流行病学进行比较.
主要方法:
- 对澳大利亚昆士兰州 (2000-2019) 所有Providencia物种BSI病例的回顾性研究.
- 从全州数据集中收集了临床和结果数据.
- 分析包括发病率,患者人口统计,并发病,感染源和病例死亡率.
主要成果:
- 在268名居民中发生了273次Providencia物种BSI; 43.2%P. rettgeri, 55.0%P. stuartii.
- 每百万人口中发生率为1.5 (P. rettgeri) 和2.1 (P. stuartii).
- P. stuartii BSI与痴呆症,胃病,半相关;P. rettgeri BSI与肝脏疾病有关. P. stuartii与下呼吸道有关,P. rettgeri与尿源有关.
- 30天病例死亡率在P. rettgeri (29.7%) 与P. stuartii (16%).相比之下,P. rettgeri (29.7%) 的病例死亡率显著更高.
结论:
- 普罗维迪安西亚物种是社区发病BSI的重要原因,特别是在老年男性中.
- P. stuartii和P. rettgeri的BSI表现出不同的临床特征和患者的并发症.
- 尽管发病率相似,但P. stuartii和P. rettgeri BSI之间存在显著的结果差异,特别是病例死亡率.
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