[高心血管风险患者的脱脂症. [来自REMEXDIS-IMSS研究的初步结果]
Maricruz Guadalupe Machuca-Loeza1, Juan Pablo Fernández-Hernández2, Maraí Xóchitl Gutiérrez-Galván3
1Instituto Mexicano del Seguro Social, Centro Médico Nacional del Bajío, Hospital de Especialidades No. 1, Servicio de Cardiología. León, Guanajuato, México.
Revista medica del Instituto Mexicano del Seguro Social
|November 11, 2024
概括
几乎一半的墨西哥社会保障研究所的受益者患有脂质失调症. 非常高风险的患者在使用他类药物时显示出更多的失脂血症,但在使用他类药物时更好地达到LDL-c目标.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 墨西哥社会保障研究所 (IMSS) 受益人中的动脉样硬化心血管疾病 (ACVD) 风险组中不存在血脂障碍和低密度脂蛋白胆固醇 (LDL-c) 目标的国家注册表.
- 这项研究解决了这一差距,专注于IMSS内的高风险和非常高风险ACVD患者群体.
研究的目的:
- 为了确定在高风险和非常高风险的ACVD患者中脱脂症的患病率.
- 评估这些患者群体的LDL-c目标和当前治疗模式的实现情况.
- 为未来的干预研究和公共卫生战略建立基线数据.
主要方法:
- 进行了一项多中心,横截面,描述性研究.
- 数据来源于墨西哥失脂症登记处的高风险和非常高风险动脉样性心血管疾病患者 (REMEXDIS-IMSS项目).
- 纳入标准侧重于符合ACVD高风险和非常高风险标准的患者.
主要成果:
- 在2022年7月至2023年3月期间,共包括6000名患者 (3289名高风险,2771名非常高风险).
- 总体而言,失脂症的发生率为49%.
- 非常高风险组的脂质失调率较高 (66.8%),急性心肌梗塞 (81.0%),胸痛 (21.9%),使用他类药物较多 (93.3%),LDL-c目标达到率较高 (72.9%).
结论:
- 脱脂症影响了研究IMSS受益人群的近一半.
- 与高风险患者相比,非常高风险的ACVD患者表现出更大的脂质失调症负担,但在二次预防中表现出更好的他类药物利用率和更好的LDL-c目标实现率.
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