怀孕,大动脉事件,新生儿和母亲的结果
Shao-Wei Chen1,2, Feng-Cheng Chang3, Chun-Yu Chen3
1Division of Thoracic and Cardiovascular Surgery, Department of Surgery, Chang Gung Memorial Hospital, Linkou Medical Center, Chang Gung University, No. 5, Fuxing Street, Guishan District, Taoyuan City 33305, Taiwan.
European heart journal
|November 11, 2024
概括
怀孕显著增加了大动脉事件的风险,导致更高的孕产妇和新生儿死亡率. 早期识别高风险妊娠对于更好的结果至关重要.
科学领域:
- 心血管医学 心血管医学
- 产科和妇科 产科和妇科
- 公共卫生 公共卫生
背景情况:
- 怀孕是一个显著的生理压力的状态.
- 怀孕期间的大动脉并发症很少见,但可能危及生命.
- 了解怀孕和大动脉事件之间的关联对于母亲和新生儿健康至关重要.
研究的目的:
- 评估怀孕和大动脉并发症之间的关联.
- 确定大动脉事件对母亲和新生儿结局的影响.
主要方法:
- 来自台湾国家医疗保险研究数据库的怀孕和分娩记录 (2000-2020) 的回顾性分析.
- 发生率比率 (IRR) 的计算,以评估大动脉事件的风险因素.
- 存活率分析以比较有或没有大动脉事件的怀孕之间的死亡率.
主要成果:
- 怀孕被确定为大动脉事件的重要危险因素 (IRR: 2.86).
- 大动脉事件的发病率在脆弱时期为每10万例怀孕1.19例.
- 在有大动脉事件的怀孕中,1年孕产妇死亡率明显高 (19.3%对比0.05%);新生儿晚期死亡率也增加 (6.3%对比0.6%).
结论:
- 怀孕与大动脉事件的风险增加有关,从孕期延伸到产后的一年.
- 怀孕期间的大动脉事件显著提高孕产妇和新生儿死亡率和发病率.
- 识别有风险的孕妇,特别是那些有高血压疾病或家族病史的孕妇,对于及时干预至关重要.
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