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Updated: Jun 7, 2025

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在心脏膜发育过程中,Manic Fringe促进由Notch信号通路介导的内皮细胞到介质细胞的过渡

Junjie Yang1,2, Zhi Wang2, Yue Zhou2

  • 1Department of Pediatric Cardiology, The Second Affiliated Hospital, Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.

Journal of molecular medicine (Berlin, Germany)
|November 11, 2024
PubMed
概括

躁狂边缘 (MFNG) 通过通过Notch信号来增强内皮到介质细胞过渡 (EndMT) 来促进心脏膜发育. 在MFNG中发生的突变会破坏这个过程,导致先天性心脏缺陷.

关键词:
反意义的形态分子寡核化物.细胞内膜介质过渡的内皮.心脏门的发展.躁狂的边缘 躁狂的边缘缺口信号通道的信号通道.整体外基因组测序的测序

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