中心得分与患有喉疼痛的儿童的快速抗原测试结果的相关性不佳
Johanna Jääskeläinen1, Marjo Renko2,3, Ilari Kuitunen2,3,4
1Institute of Clinical Medicine and Department of Pediatrics, University of Eastern Finland, Yliopistonranta 2, 70211, Kuopio, Finland. johajaa@student.uef.fi.
European journal of pediatrics
|November 11, 2024
概括
Centor评分没有有效地预测儿童A组 estreptococcal喉炎的快速抗原测试结果. 微生物学测试对于准确的诊断至关重要,因为单独的Centor得分是没有用处的.
科学领域:
- 儿科 儿科 儿科
- 传染性疾病 传染性疾病
- 诊断的准确性 诊断的准确性
背景情况:
- 芬兰当前护理指南建议在儿童中对疑似A型 estreptococcal (GAS) 喉炎进行快速抗原测试,Centor评分≥3.
- Centor评分是一个临床工具,用于区分GAS喉炎和病毒性喉炎.
研究的目的:
- 评估芬兰儿童中GAS喉炎的Centor得分和快速抗原测试阳性之间的关联.
- 评估Centor得分在指导GAS喉炎诊断中的诊断实用性.
主要方法:
- 一项回顾性单一中心研究包括464名年龄在0-15岁的儿童,他们被诊断患有急性喉炎.
- 从电子健康记录中提取了Centor得分,快速抗原测试,喉培养和C反应蛋白 (CRP) 水平的数据.
- 统计分析涉及比较比例和计算置信区间.
主要成果:
- 在Centor得分和快速抗原测试对GAS的阳性之间没有发现显著的关联.
- 对于快速抗原测试阳性的Centor得分≥3的灵敏度为22.3%,特异性为79.0%.
- 17.1%的快速抗原测试阴性患者有阳性喉培养;Centor得分与CRP相关,但CRP没有预测阳性抗原测试.
结论:
- 单独的Centor评分在诊断儿童中疑似链球菌喉炎时具有有限的实用性.
- 微生物学测试对于准确的诊断至关重要,并且不应使用CRP水平来区分细菌和病毒性喉炎.
相关概念视频
01:30Acute Pharyngitis
447
Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
447
01:30Tonsillitis I: Introduction
208
Tonsillitis is inflammation of the tonsils, which are two lymphoid tissue masses at the back of the throat. This condition can cause discomfort and irritation in the throat.
Etiology
Three primary contributing factors have been identified.
Etiology
Three primary contributing factors have been identified.
208
01:20Spearman's Rank Correlation Test
683
Spearman's rank correlation test, also known as Spearman's rho, is a nonparametric method for assessing the strength and direction of association between two variables. This test is particularly valuable when the data distribution is unknown or when the assumption of normality does not hold. Named after the English psychologist and statistician Dr. Charles Edward Spearman, it serves as the nonparametric counterpart to Pearson's correlation coefficient.
Spearman's test calculates...
Spearman's test calculates...
683
01:20Sputum Studies II: Culture and Sensitivity
259
Description
Sputum culture and sensitivity is a medical procedure used to diagnose bacterial infections in the respiratory tract and select the most appropriate antibiotics for treatment. This process involves analyzing sputum samples of thick and opaque secretions produced in the lungs and airways. These samples are collected from patients and then sent to the laboratory for analysis.
The test can identify various pathogens responsible for respiratory infections, including Streptococcus,...
Sputum culture and sensitivity is a medical procedure used to diagnose bacterial infections in the respiratory tract and select the most appropriate antibiotics for treatment. This process involves analyzing sputum samples of thick and opaque secretions produced in the lungs and airways. These samples are collected from patients and then sent to the laboratory for analysis.
The test can identify various pathogens responsible for respiratory infections, including Streptococcus,...
259
01:26Tonsillitis II: Management
103
This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.
103