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Updated: Jun 7, 2025

Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
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洞察新型硫甲酸衍生物作为抗癌碳酸酶抑制剂

Rehab F Ahmed1, Walaa R Mahmoud2, Nagwa M Abdelgawad2

  • 1Pharmaceutical Chemistry Department, Faculty of Pharmacy, Cairo University, Kasr El-Aini St., Cairo, 11562, Egypt. rehab.abdelmoneim@pharma.cu.edu.eg.

Molecular diversity
|November 11, 2024
PubMed
概括

合成了新的pyrazole衍生物,并测试了它们抑制与癌症相关的人类碳酸 anhydrase (hCA) 酶的能力. 有前途的化合物显示出显著的抗癌活性,并在癌细胞中诱导了亡,这需要进一步的研究.

关键词:
乙醇胺的使用方法碳酸无水酶抑制的抑制分子建模分子建模硫甲烯 (Sulfamoylphenyl) 是一种硫甲的化合物.

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