指性瘤患者的第二次原发性癌症:基于登记的队列研究
Rayan Nikkilä1,2,3,4, Elli Hirvonen3, Aaro Haapaniemi1
1Department of Otorhinolaryngology - Head and Neck Surgery, University of Helsinki, Helsinki University Hospital, P.O. Box 263, Helsinki, FI-00029 HUS, Finland.
BMC cancer
|November 11, 2024
概括
喉癌患者患第二种原发性癌症的风险增加了80%,持续数十年. 早期检测和生活方式的改变对于管理这种高风险至关重要.
科学领域:
- 在瘤学瘤学.
- 癌症流行病学 癌症流行病学
背景情况:
- 有限的欧洲数据存在于喉癌 (PC) 患者的第二次原发性癌症 (SPC) 风险.
- 本研究通过从欧洲的角度检查SPC风险来解决代表人数不足的问题.
研究的目的:
- 评估最初诊断为喉癌的个体中SPC的亚位点特异性风险.
- 为了提供一个基于欧洲的SPC风险后喉癌的风险分析.
主要方法:
- 从1953年到2021年,芬兰进行了一项基于登记的队列研究.
- 在患有口腔喉癌 (OPC),鼻癌 (NPC) 和鼻癌 (HPC) 患者的SPC中计算了标准化发病率 (SIR).
主要成果:
- 在4701名PC患者中,11.9%患有SPC,男性 (12.3%) 的发病率高于女性 (10.9%).
- PC患者的SPC风险总体增加了80% (男性的SIR为1.83,女性为1.89).
- 观察到特定SPC部位的风险增加,包括口腔/喉,呼吸,消化,大脑和血淋巴体器官,因主要喉部位而异.
结论:
- 喉癌患者面临着显著增加和长期发展第二种原发性癌症的风险.
- 医疗保健提供者应为患者提供关于生活方式修改的建议,并监测SPC.
- 意识到持续的SPC风险对于长期患者管理和幸存者护理至关重要.
关键词:
癌瘤的癌症是什么头癌是头部和部的癌症.低喉下垂体 (Hypopharynx) 是一个低喉.鼻和鼻 (Nasopharynx) 是一个鼻和鼻.耳鼻喉 (oropharynx) 是一个喉 (pharynx) 是一个神经系统.第二个初级初级.更多相关视频
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