塔卡亚苏的动脉炎与结核病相关:一项回顾性研究
Ana Luisa Souza Pedreira1,2, Maria de Lourdes Castro de Oliveira Figueiroa3, Mariana Oliveira Miranda3
1Hospital Universitário Professor Edgard Santos - Universidade Federal da Bahia, Salvador, Bahia, Brazil. anapedreira@bahiana.edu.br.
Advances in rheumatology (London, England)
|November 11, 2024
概括
塔卡亚苏动脉炎 (TA) 患有结核病 (TB) 感染的患者,包括潜伏结核病感染 (LTBI),体重减轻增加,大动脉动脉瘤和扩张的患病率更高,特别是在腹腔大动脉.
科学领域:
- 血管炎症和传染性疾病
- 风湿病学和免疫学
背景情况:
- 塔卡亚苏动脉炎 (TA) 和结核病 (TB) 具有重叠的组织病理学和免疫学特征.
- 之前的研究表明,在同时或过去患有结核病感染的TA患者中,临床和血管学差异存在.
- 患有结核病史的TA患者往往呈现出更多的宪法症状和大动脉结构损伤.
研究的目的:
- 根据活跃或潜伏结核病 (TB) 感染的存在或不存在,对被诊断患有塔卡亚苏动脉炎 (TA) 的患者的临床和放射性特征进行比较.
- 确定与TA患者结核病共感染相关的特定特征.
主要方法:
- 从巴西东北部的第三级推中心治疗的TA患者的数据进行了回顾性分析.
- 2017年1月至2022年6月期间收集的患者数据.
- 在TA患者和没有结核病 (活跃或潜伏) 之间比较了临床特征.
主要成果:
- 在50名符合条件的TA患者中,20名 (40%) 患有结核病 (6名活跃结核病,14名潜伏结核病感染).
- 在患有结核病的TA患者中,体重减轻明显更常见 (p=0.005).
- 腹腔大动脉卷入 (p=0.013),扩张 (p=0.009) 和动脉瘤 (p=0.027) 在TA结核病患者中明显更频繁.
结论:
- 与肺结核同时感染的高雅苏动脉炎患者出现大动脉扩张和动脉瘤的发病率较高.
- 腹腔大动脉是TA结核病患者中这些血管异常最常受到影响的部位.
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