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Updated: Jun 7, 2025

High-throughput Quantitative Real-time RT-PCR Assay for Determining Expression Profiles of Types I and III Interferon Subtypes
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I型干扰素驱动细胞状态对TCR刺激无效,可能阻碍癌症中有效的T细胞分化

Dillon Corvino1, Martin Batstone2,3, Brett G M Hughes2,3

  • 1Tumor-Immunobiology, Institute for Experimental Oncology, University Hospital Bonn, Bonn, Germany.

European journal of immunology
|November 12, 2024
PubMed
概括

研究人员发现了一种新的CD8+T细胞子集,称为干扰素刺激基因 (ISG) 丰富细胞,在HPV阴性头支状细胞癌中. 这些细胞虽然在转录上是惰性的,但可能会影响抗瘤免疫力,并影响治疗策略.

关键词:
这是CD8+ T细胞.在HNSCC的TILs中.第一种类型的IFN IFN.我们的 scRNAseqq.scTCRseqq 的意思是什么?

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