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相关概念视频

Factors Influencing Drug Absorption: Pharmaceutical Parameters01:28

Factors Influencing Drug Absorption: Pharmaceutical Parameters

121
Solid dosage forms such as tablets and capsules undergo rigorous manufacturing processes to ensure stability and effectiveness. Their dissolution and absorption properties are influenced significantly by the choice of excipients (inactive ingredients that serve various roles in the formulation), and the methodology applied during production. The manufacturing parameters, such as compression force and granulation techniques, significantly affect dissolution rates. Elevated compression forces...
121
Factors Affecting Dissolution: Drug Permeability, Stability and Stereochemistry01:20

Factors Affecting Dissolution: Drug Permeability, Stability and Stereochemistry

178
Orally administered drugs primarily enter the systemic circulation via passive diffusion through the intestinal membranes. The drug's absorption is influenced by drug stability in the gastrointestinal GI tract, membrane permeability, the surface area available for absorption, luminal drug concentration, and residence time in the lumen. Drug permeability can be enhanced by adjusting the lipophilicity, polarity, or molecular size of the drug, promoting its passive transport across intestinal...
178

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相关实验视频

Updated: Jun 7, 2025

Extraction of Plant-based Capsules for Microencapsulation Applications
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Extraction of Plant-based Capsules for Microencapsulation Applications

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开发大麻二醇配方的微封装技术:一篇综述

Ariel Gustavo Garro1,2, Soledad Ravetti2,3, Sofía Gisella Brignone4

  • 1Ministerio de Producción, Ciencia e Innovación Tecnológica de la Provincia de Córdoba, Córdoba, CP 5004, Argentina.

Therapeutic delivery
|November 12, 2024
PubMed
概括
此摘要是机器生成的。

微封装通过改善其不良的生物可用性和水溶性来增强大麻 (CBD) 的治疗潜力. 这种技术为优化CBD配方和管理挑战提供了一个有希望的解决方案.

关键词:
在Cannabidiol中使用.大麻大麻大麻大麻大麻大麻大麻大麻微装封装是一种微装封装.自然产品是自然产品的产品.制药技术 制药技术 制药技术

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Preparation and Characterization of Individual and Multi-drug Loaded Physically Entrapped Polymeric Micelles
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Preparation and Characterization of Individual and Multi-drug Loaded Physically Entrapped Polymeric Micelles

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相关实验视频

Last Updated: Jun 7, 2025

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Ultrasonic-Assisted Extraction of Cannabidiolic Acid from Cannabis Biomass
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科学领域:

  • 药理学和制药科学 药理学和制药科学
  • 生物技术是生物技术.
  • 自然产品化学 自然产品化学

背景情况:

  • Cannabidiol (CBD) 是来自Cannabis sativa L. 的,它表现出没有精神活性作用的治疗性质.
  • CBD与内分泌系统相互作用,影响情绪,疼痛和免疫反应.
  • 低生物可用性和水溶性限制了CBD的临床疗效和管理.

研究的目的:

  • 审查CBD的各种微封装技术.
  • 分析不同微封装方法的优点和局限性.
  • 探索对优化CBD配方的影响.

主要方法:

  • 关于CBD微封装技术的综合文献综述.
  • 对CBD微封装方法的已公布数据的分析.
  • 对配方优化策略的评估.

主要成果:

  • 微封装显著提高了CBD的生物可用性和可溶性.
  • 诸如喷雾干燥,脂质体封装和纳米粒子形成等各种技术是有效的.
  • 每种方法在可扩展性,成本和封装效率方面都有独特的优势和局限性.

结论:

  • 微封装是一种可行的策略,可以克服CBD的配方挑战.
  • 优化的微封装CBD配方对改善治疗效果具有显著的前景.
  • 需要进一步的研究来完善大规模,经济高效的生产方法.