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药剂师主导的医院干预减少了医院出院后无意的患者产生的药物差异
Frontiers in pharmacology
|November 12, 2024
概括
药剂师主导的药物调整大大减少了医院出院后患者无意造成的药物错误. 这种干预措施改善了出院后的药物管理和患者安全.
科学领域:
- 临床药房 临床药房
- 患者安全 患者安全
- 药物管理 药物管理
背景情况:
- 医院出院时的药物调整减少了错误,但其对出院后管理的影响尚不清楚.
- 在出院30天后,患者产生的药物异常需要调查.
- 药剂师干预对患者引起的差异的影响需要评估.
研究的目的:
- 为了调查患者在医院出院30天后产生的药物异常的发生率.
- 评估药剂师主导的药物调和和患者咨询对患者引起的临床重要差异的影响.
主要方法:
- 一个务实的,前性的,受控的临床试验,涉及254名成年患者.
- 干预组接受了由药剂师领导的和解 (入院/出院) 和咨询.
- 通过通过患者访谈,通过比较出院处方与30天出院后治疗发现的差异.
主要成果:
- 25.3%的药物在出院30天后有差异; 52.4%是患者产生的.
- 在非故意的 (45.4%) 比故意的 (18.7%) 患者变化中,临床重要差异更高.
- 干预显著减少了非故意的患者产生的差异 (OR 0.204),但不是故意的差异.
结论:
- 出院后患者产生的差异是常见的,并且可能是有害的.
- 药剂师主导的干预措施有效地减少了出院后早期的药物差异.
- 研究结果支持开发服务,以加强住院后患者药物管理.
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