吸毒者肺动脉高血压相关住院病例的趋势和模式:长达十年的研究
Amanda Husein1, Jolie Boullion1, Md Ismail Hossain1
1Department of Medicine, Louisiana State University Health Sciences Center at Shreveport, Shreveport, LA, United States.
Frontiers in cardiovascular medicine
|November 12, 2024
概括
在全国范围内,使用甲基胺的肺动脉高血压 (PAH) 病例升了9.2倍. 这一趋势不成比例地影响男性,老年人和特定的人口统计数据,突显了迫切的公共卫生问题.
科学领域:
- 心脏病学 心脏病学
- 肺部病理学 肺部病理学
- 公共卫生 公共卫生
- 成 药物 药物 药物 药物
背景情况:
- 肺动脉高血压 (PAH) 是一种严重的,渐进的疾病,导致心力衰竭.
- 甲基胺使用是PAH的新兴因素,但最近的趋势和患者人口统计数据是未知的.
研究的目的:
- 分析PAH患者的全国趋势和人口统计数据,同时使用或不使用甲基胺.
- 确定与甲基胺使用者的PAH住院病例增加相关的社会人口学因素.
主要方法:
- 使用国家住院样本 (NIS) 数据库从2008年到2020年.
- 使用ICD-9和ICD-10代码来识别疾病.
- 应用描述性统计,奇方和t测试,趋势分析 (科克兰-阿米塔奇) 和通用线性模型.
主要成果:
- 随着同时使用甲基胺的PAH住院病例增加了9.2倍.
- 入院患者主要是男性 (59.16%),年龄在41-64岁之间 (45.77%),白人 (68.64%),来自西部 (53.09%),医疗补助 (50.48%) 和低收入 (<25,000美元).
- 与非使用者相比,甲基胺使用者在PAH住院的调整流行率 (PR) 显著更高,为32.19,因各种人口统计和临床因素增加了风险.
结论:
- 揭示了与甲基胺使用相关的PAH在全国显著增加.
- 突出了需要有针对性的研究和政策干预的特定弱势社会人口群体.
- 强调需要进一步研究这种患者队列的机制和管理.
相关概念视频
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