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中性细胞外细胞陷在口腔疾病中

Pengfei Gao¹, Jun Zhou², Lu Sun³

¹Department of Periodontology, Suzhou Stomatological Hospital, Suzhou, Jiangsu, China.

|November 12, 2024

概括

中性细胞外细胞陷 (NETs) 对于对抗微生物至关重要,但也可能导致炎症. 需要进一步的研究来了解NET在牙周炎等口腔疾病中的复杂作用.

科学领域:

免疫学免疫学免疫学
口腔病理学口腔病理学

背景情况:

中性细胞外细胞陷 (NETs) 是天生的免疫系统的关键组成部分.
网络参与宿主防御微生物入侵和组织平衡.

研究的目的:

审查和总结有关中性粒细胞外细胞陷 (NETs) 的当前知识.
阐明NET在各种口腔疾病的发病过程中的关键作用.

主要方法:

使用PubMed和Web of Science进行了全面的文献审查.
分析了专注于NETs诱导,形成,功能和参与口腔疾病的研究.

主要成果:

网具有双重作用,通过抗炎作用对抗病原体,同时也可能导致炎症.
网与其他免疫细胞相互作用,并对各种刺激作出反应,包括病原体,宿主媒介和药物.
NETs显著影响牙周炎,牙内感染,口腔粘膜疾病和面瘤的进展.

结论:

网的保护性和有害性之间的平衡对感染和炎症的结果至关重要.
进一步研究NET在各种口腔疾病中的特定作用对于治疗进步至关重要.

关键词:

在OSSC中,OSSC是OSSC的组成部分.中性粒细胞外细胞陷口腔粘膜疾病口腔粘膜疾病牙周炎是指牙周炎的一种疾病.

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